Texas hosts a vibrant pharmaceutical and biotech ecosystem, with over 260 companies engaged in drug development, manufacturing, and therapies for health challenges ranging from chronic diseases to critical care. Moreover, there are multiple research institutions with substantial investments to drive innovations in pharmaceuticals, biotechnology, and therapeutics. The pharma industry is a key driver of the robust economy of Texas, generating over 116,000 direct jobs. Texas is swiftly becoming a hub of drug development, based on cutting-edge research and skilled workforce.
Texas leverages 35 foreign trade zones and a vast freight network to support global pharma supply chains. Major centers of pharma industry in the state of Texas include Dallas, Houston, Austin, and San Antonio. Let’s have a look at the top 5 pharma companies in Texas.

1. Mystic Pharmaceuticals Inc.
Mystic Pharmaceuticals Inc., founded in the year 2003, is an integrated specialty pharma company, headquartered in Austin, Texas. The company specializes in innovative drug-delivery technologies, with emphasis on precision unit-dose systems that enhance patient compliance, efficacy, and safety.
Mystic is proficient in developing proprietary platforms for targeted drug administration, such as intranasal and nose-to-brain delivery, and precision dosing for eye, oral, ear, and dermal therapies. Signature products developed by the company include ArrowFish Nasal Delivery System and MystiLol.
- Address: 2006, Windy Terrace, Cedar Park, Austin, TX 78613
2. Neos Therapeutics Inc.
Neos Therapeutics Inc., founded in the year 1994, is specialty pharmaceutical company, headquartered in Grand Prairie, Texas. The company leverages proprietary drug delivery technologies, including microparticle-based oral disintegrating tablets, to create innovative patient-friendly formulations that improve compliance and efficacy.
Key products by Neos Therapeutics include Amphetamine extended-release ODT to treat ADHD symptoms with once-daily dosing, Methylphenidate extended-release ODT to treat inattention and hyperactivity, and Amphetamine extended-release suspension alternative for easier administration. The company’s facility in Grand Prairie supports end-to-end manufacturing and R&D.
- Address: 2940, N. Hwy, 360 Grand Prairie, Texas 75050
3. Lexicon Pharmaceuticals
Lexicon Pharmaceuticals, founded in the year 1995, is a biopharmaceutical company, headquartered in The Woodlands, Texas. The company takes genetic-driven approaches to discover, develop, and commercialize innovative medicines. It is particularly known for its proprietary platform, named Genome5000, which has analyzed around 5,000 genes to identify over 100 therapeutic targets, covering needs in areas like heart failure, obesity, neuropathic pain, diabetes and others.
Lexicon focuses on precision medicine derived from genetic insights, targeting neurology, endocrinology, and cardiometabolic disorders. It has multiple marketed products and a robust pipeline.
- Address: 2445, Technology Forest Boulevard, The Woodlands, Texas 77381
4. RadioMedix Inc.
RadioMedix Inc., established in the year 2006, is a Houston-based biotechnology company specializing in the development of innovative targeted radiopharmaceuticals for cancer diagnosis, monitoring, and therapy. It utilizes radioactive isotopes like Actinium-225, Lead-212, Gallium-68 and more to address cancers like neuroendocrine cancer and prostate cancer. The company develops cutting-edge diagnostic and therapeutic solutions through next-generation PET imaging agents, and targeted alpha and beta therapies.
RadioMedix Inc. operates a 27,000 square feet facility in Humble, Texas. This facility is used for a number of purposes, including drug discovery, pre-clinical evaluation, and large-scale commercial manufacturing.
- Address: 9701 Richmond Avenue, Suite 222, Houston, Texas 77042
5. Humco
Humco is a pharmaceutical compounding and specialty products company, headquartered in Austin, Texas. Founded in the year 1872, it is one of the oldest pharmaceutical companies still in operation in the United States. The company specializes in developing and manufacturing pharmaceutical bases for ointments, gels, creams, and liquid suspensions, sweeteners and flavoring agents for pediatric and geriatric formulations, preservative systems and emulsifiers, and specialty vehicles for oral, topical, and rectal delivery.
Humco has its own state-of-the-art cGMP-compliant manufacturing facility located in Texarkana, Texas.
- Address: 201 W 5th St, Floor 12, Austin, Texas 78701
Conclusion
Pharma industry in Texas is defined by a business-friendly environment, strategic investments in manufacturing and innovation, and world-class research. Employment growth in the pharmaceutical industry of the state has outpaced the national average in the recent years.
